The Museum, which has a Metrobus stop for Routes 56 and 24 at its front door, is in the heart of downtown Coral Gables. Next door to the Museum is Books & Books, a successful independent bookseller and neighbors include the Coral Gables Art Cinema; the Columbian Consulate and a number of locally owned and operated businesses, restaurants and hotels. The Museum is easily accessed from the Douglas Road Metrorail Station. The Coral Gables Ponce de Leon Trolley, which stops at the Douglas Road Station travels through downtown Coral Gables and stops just one block from the Museum at Aragon Avenue. Convenient parking for Museum visitors is located at the City of Coral Gables Museum Parking Garage at 250 Aragon Avenue.
The Museum is a designated Bike-Friendly Business and has 6 bike racks on site for visitors who prefer biking.